It will boil down to two predominant factors that control how a virus behaves in a population: the virus’s biology and the immunity of the host population.
Endemic viruses are those that have constant presence within a geographical area. Such viruses are all around us, though they vary by location. Examples in Europe and North America include the rhinovirus (a cause of the common cold) and influenza virus, while the dengue and chikungunya viruses are endemic in many Asian countries.
Endemic diseases are often milder, but it’s important to note that this isn’t always the case. Flu, for instance, is estimated to cause up to 810,000 hospitalizations and 61,000 deaths annually in the US.
There are currently four endemic coronaviruses that, for most people, just cause a cold. Whether SARS-CoV-2, the virus that causes COVID-19, will join them will be down to two predominant factors that control how a virus behaves in a population: the virus’s biology and the immunity of the host population.
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